BIOL 01. Cellular and Molecular Biology
Team taught. An introduction to the study of living systems illustrated by examples drawn from cell biology, biochemistry, genetics, microbiology, neurobiology, and developmental biology.
Prerequisites
No prerequisites.
Can we describe complex biological networks (e.g. transcription regulation, signal transduction, neuronal networks) in terms of basic building block circuits? Are there simple rules that allow us to understand fundamental biological processes such as cell-environment interactions, embryonic development, and organismal patterning? Systems Biology is an innovative, cross-disciplinary approach that will train students in the basic skills to tackle these fundamental biological questions and predict the dynamics of complex biological systems. This will be achieved through hands-on training in biological, computational, and quantitative methods, and through reading of primary literature. In the laboratory, students will work with diverse biological systems, including bacteria, eukaryotic cells, Hydra, and planarians, and design and execute independent research projects.
Prerequisites
BIOL 001, STAT 011, and MATH 015.
BIOL 126. Biomechanics in Development and Regeneration
Biomechanics investigates the interplay of mechanical forces and biological processes across scales, from nanomachines to whole organisms. This interplay is an important mechanism influencing key processes in embryonic development, disease, and regeneration of animals. Research in biomechanics also serves as inspiration for bioengineering and regenerative medicine. In this seminar, students will explore the primary literature in biomechanics through student-led discussions. Focus areas may include development, regeneration, or animal behavior.
Prerequisites
BIOL 027.
BIOL 117. Trends in Pharmacology
Pharmacology investigates the mechanisms of drug effects from the molecular level to the whole animal. We will examine the mode of action of drugs, learn about drug design and development, xenobiotic metabolism and the cellular and organismal responses to drug exposure. Students will explore the field of pharmacology through student-driven discussion of primary literature. Topics will encompass landmark pharmacology papers as well as new approach methods.
Prerequisites
STAT 011, CHEM 010, and one of the following:
CHEM 038, BIOL 014, BIOL 020, BIOL 022, BIOL 027.
BIOL 129. Developmental Neurotoxicology
In this seminar students will explore the field of developmental neurotoxicology, with an emphasis on alternative toxicology models and computational approaches. The seminar will encompass student-driven discussion of primary literature, ranging from landmark toxicology papers to new approach methods. Course content emphasizes statistical and quantitative methods.
Prerequisites
At least one of: BIOL 027, BIOL 022, BIOL 029
Recommended: STAT 021.